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Each year the Heart editorial team selects the most meritorious research papers to receive the Heart Best Research Paper Award.. We are pleased to announce the winner and finalists for the Heart Best Research Paper Award 2024 in recognition of high quality and clinical impact.
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Cardiovascular alterations are common in patients who had ischaemic stroke, haemorrhagic stroke and other acute brain disorders such as seizures. These cardiac complications are important drivers of morbidity and mortality and comprise blood-based detection of cardiomyocyte damage, ECG changes, heart failure and arrhythmia. Recently, the concept of a distinct ‘stroke-heart syndrome’ has ...
Lifetime effects and cost-effectiveness of statin therapy for older ...
Background Cardiovascular disease (CVD) risk increases with age. Statins reduce cardiovascular risk but their effects are less certain at older ages. We assessed the long-term effects and cost-effectiveness of statin therapy for older people in the contemporary UK population using a recent meta-analysis of randomised evidence of statin effects in …
Management of heart failure with reduced ejection fraction
### Learning objectives Heart failure is a syndrome characterised by a triad of symptoms, signs and objective evidence of cardiac dysfunction. The syndrome is divided into subtypes based on left ventricular ejection fraction (LVEF). Where the LVEF is below 40% this is termed heart failure with reduced ejection fraction (HFrEF). This differentiation …
Global longitudinal strain: clinical use and prognostic ... - Heart
### Learning objectives Non-invasive evaluation of left ventricular (LV) systolic function by echocardiography remains one of the most pivotal measures in clinical cardiology. Although conventionally quantified by means of LV ejection fraction (LVEF), it has become evident that this parameter is subject to a number of limitations. LVEF can …
Bradyarrhythmias in patients with atrial fibrillation | Heart
The increasing burden of atrial fibrillation (AF) and significant morbidity/mortality associated with this arrhythmia encourage screening it in clinical practice, as recommended in current guidelines. It means opportunistic screening (in patients over 65 years) or systematic screening (in people above 75 years) by using clinical examination, followed by an ECG, 24-hour ECG monitoring or ...
Treating patients with ventricular ectopic beats | Heart
Ventricular ectopic beats (VEBs) are commonly seen in daily clinical practice. They are largely asymptomatic but can cause upsetting symptoms in some patients. In normal hearts, their occurrence is usually associated with no clinical significance. However, there are occasions where the presence of VEBs signifies a susceptibility towards more sinister arrhythmias, especially when heart disease ...
Left ventricular dysfunction: causes, natural history, and ... - Heart
Left ventricular dysfunction (LVD) with subsequent congestive heart failure (CHF) constitutes the final common pathway for a host of cardiac disorders. Coronary artery narrowing or ischaemic heart disease is the dominant cause of heart failure and is often associated with acute or prior myocardial infarction. The remaining aetiologies include cardiomyopathy, hypertension, and a …
Management of premature ventricular complexes | Heart
Introduction. Premature ventricular complexes (PVCs) are the most common arrhythmias in daily practice. At the cellular level, ventricular myocytes spontaneously depolarise to create an extrasystole ‘out of sync’ with the cardiac cycle. 1 The prevalence depends on the characteristics and comorbidities of the population, the method by …
Nationwide burden of sudden cardiac death among patients with …
Background Patients with psychiatric disorders have increased all-cause mortality compared with the general population. Previous research has shown that there is a fourfold increased risk of sudden cardiac death (SCD) among the young. Objective To investigate the incidence of SCD in patients with psychiatric disorders aged 18–90 years …