gut.bmj

Blockade of transforming growth factor β upregulates T-box transcription factor T-bet, and increases T helper cell type 1 cytokine and matrix metalloproteinase-3 production in ...

1 Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London School of Medicine and Dentistry, London, UK 2 Division of Infection, Inflammation and Repair, University ...
gut.bmj

PTU-111 Nutrition in cirrhosis: why we must save them from turning to (l)dust?

Introduction Undernutrition in cirrhotic patients is often poorly recognised until late-stage. The UK screening tool, the Malnutrition Universal Screening Tool, is flawed for patients with ...
gut.bmj

OTH-01 A complex lower gastrointestinal polyp MDT improves evidence-based decision making and efficiency of endoscopy scheduling

Introduction Demand for lower gastrointestinal (LGI) endoscopy in the UK has doubled (1). In an increasingly ageing and co-morbid population, multi-disciplinary team (MDT) discussion is necessary to ...
gut.bmj

An updated Asia Pacific Consensus Recommendations on colorectal cancer screening

Objective Since the publication of the first Asia Pacific Consensus on Colorectal Cancer (CRC) in 2008, there are substantial advancements in the science and experience of implementing CRC screening.
gut.bmj

IBD and arthropathies: a practical approach to its diagnosis and management

1 Department of Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, The Netherlands 2 Department of Rheumatology, Leiden University Medical Center, Leiden, The Netherlands ...
gut.bmj

Type of pain, pain-associated complications, quality of life, disability and resource utilisation in chronic pancreatitis: a prospective cohort study

4 Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan, USA 5 Department of Medicine, Indiana University Medical Center, Indianapolis, Indiana, USA 6 Digestive Disease Center, ...
gut.bmj

Pharmacological inhibition of the chemokine CCL2 (MCP-1) diminishes liver macrophage infiltration and steatohepatitis in chronic hepatic injury

1 Department of Medicine III, University Hospital Aachen, Aachen, Germany 2 Institute of Pathology, University Hospital Aachen, Aachen, Germany 3 Institute of Pathology, University Bonn, Bonn, Germany ...
gut.bmj

OTU-12 Validation of Edinburgh dysphagia score in a national evaluation of upper GI cancer 2ww pathway

Introduction British Society of Gastroenterology has recommended to use the Edinburgh Dysphagia Score (EDS) (with a cut off ≥ 3.5) to risk stratify dysphagia referrals during the endoscopy COVID ...
gut.bmj

Changes in expression and distribution of claudin 2, 5 and 8 lead to discontinuous tight junctions and barrier dysfunction in active Crohn’s disease

1 Department of Gastroenterology, Infectious Diseases and Rheumatology, Charité, Campus Benjamin Franklin, Berlin, Germany 2 Department of Clinical Physiology, Charité, Campus Benjamin Franklin, ...
gut.bmj

Alcohol consumption, cigarette smoking and risk of subtypes of oesophageal and gastric cancer: a prospective cohort study

Objective: Alcohol consumption and cigarette smoking may be differentially associated with oesophageal squamous cell carcinoma (OSCC), oesophageal adenocarcinoma (OAC), gastric cardia adenocarcinoma ...
gut.bmj

Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and ...

5 Servicio de Aparato Digestivo, Hospital Donostia, San Sebastian, Spain 6 Servicio de Aparato Digestivo Hospital La Fe, Valencia, Spain 7 Servicio de Aparato Digestivo, Hospital de Asturias, Oviedo, ...
gut.bmj

P37 Hepatic ACE2 expression is upregulated in early NAFLD and in patients who died with severe COVID-19: a histological analysis

Non-alcoholic fatty liver disease (NAFLD) has been identified as a predictor of liver injury in patients hospitalised with coronavirus disease 2019 (COVID-19) and there are emerging reports of ...