BMJ

FOXP3 expression in blood, synovial fluid and synovial tissue during inflammatory arthritis and intra-articular corticosteroid treatment

Objective: To analyse the distribution of FOXP3+CD25+CD4+ regulatory T cells (Treg) in peripheral blood, synovial fluid and tissue of patients with rheumatic disease during relapse and after local ...
BMJ

The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats

3 Rheumatology Unit, Department of Medicine at the Karolinska University Hospital Solna, Sweden 4 Division of Rheumatology, Department of Internal Medicine 3, Medical University of Vienna, Vienna, ...
BMJ

Combination therapy with sulfasalazine and methotrexate is more effective than either drug alone in patients with rheumatoid arthritis with a suboptimal response to ...

Background: Optimal use of disease-modifying antirheumatic drugs (DMARDs) in rheumatoid arthritis is vital if progression of disease is to be reduced. Methotrexate (MTX) and sulfasalazine (SASP) are ...
BMJ

Etanercept therapy in rheumatoid arthritis and the risk of malignancies: a systematic review and individual patient data meta-analysis of randomised controlled trials

Division of Rheumatology and Department of Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota, USA Purpose: Tumour necrosis factor (TNF) plays an important role in inflammation ...
BMJ

Tendon involvement in the feet of patients with gout: a dual-energy CT study

1 Bone and Joint Research Group, Department of Medicine, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand 2 Department of Anatomy with Radiology, Faculty of ...
BMJ

Thickness of human articular cartilage in joints of the lower limb

OBJECTIVES (a) To determine the topographical variations in cartilage thickness over the entire surfaces of cadaveric lower limb joints, and (b) to examine the correlations between: cartilage ...
BMJ

Physiotherapy for anterior knee pain: a randomised controlled trial

OBJECTIVE To determine the efficacy of the individual components of physiotherapy in subjects with anterior knee pain. METHODS An observer blind, prospective, factorial design randomised controlled ...
BMJ

Methotrexate reduces immunogenicity in adalimumab treated rheumatoid arthritis patients in a dose dependent manner

2 Department of Internal Medicine, VU University Medical Center, Amsterdam, The Netherlands 3 Department of Immunopathology, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, ...
BMJ

Incidence trend of five common musculoskeletal disorders from 1990 to 2017 at the global, regional and national level: results from the global burden of disease study 2017

Correspondence to Professor Lingyun Sun, Department of Rheumatology and Immunology, Nanjing University Medical School Affiliated Nanjing Drum Tower Hospital, Nanjing 210008, China; ...
BMJ

Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial

Background The efficacy of oral prednisolone in patients with active ankylosing spondylitis (AS) has not been studied to date. Methods In this double-blind, randomised, placebo-controlled trial, ...
BMJ

Inflammation in ankylosing spondylitis: a systematic description of the extent and frequency of acute spinal changes using magnetic resonance imaging

Background: Magnetic resonance imaging (MRI) is increasingly used to detect inflammation in the spine of patients with ankylosing spondylitis (AS). Objectives: To detect differentially the presence ...
BMJ

Effects of belimumab, a B lymphocyte stimulator-specific inhibitor, on disease activity across multiple organ domains in patients with systemic lupus erythematosus: combined ...

11 Johns Hopkins University, School of Medicine, Baltimore, Maryland, USA Correspondence to Susan Manzi, Allegheny Singer Research Institute, West Penn Allegheny Health System, Temple University ...