JERUSALEM — Israel said Friday it will intensify its 22-month war with Hamas by taking over Gaza City, drawing a dismissal from the militant group and renewed international calls to end the conflict while stirring fears for Palestinian civilians and Israeli hostages still held in Gaza.

The U.N. High Commissioner for Human Rights, Volker Turk, said “this further escalation will result in more killing, more unbearable suffering, senseless destruction."

Israel’s security cabinet has voted to expand the war in Gaza, marking a major escalation at a time when it is under intense domestic and international pressure to end the conflict.