Houston guard Milos Uzan is expected to turn pro, but Emanuel Sharp and Joseph Tugler could return to fortify a Cougars team that easily could have won Monday night. The Gators have 20-1 odds to repeat, tied for the seventh best with five other teams (BYU, Kentucky, Arkansas, Kansas and Alabama).

What are Final Four odds now? What to know about Houston Cougars vs Duke Blue Devils point spread, moneyline, over/under for March Madness betting.

Madness, the United States' beloved betting holiday, reaches a crescendo on Monday when Houston face Florida after a thrilling men's final four that injected life into a tournament which largely stuck to the script in the early rounds.