Eddy Pineiro redeemed himself in the 49ers' MNF matchup against the Indianapolis Colts with a textbook field goal after a ...

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the ...

The Colts’ loss clinched playoff spots for the Bills and Chargers. The 49ers had already clinched their spot in the NFC, and ...

Brock Purdy and the San Francisco 49ers earned a statement 48–27 road win over Philip Rivers and the Indianapolis Colts on Monday Night Football, as both quarterbacks put on an entertaining aerial ...

The San Francisco 49ers have beaten the Indianapolis Colts 48-27 on “Monday Night Football” behind Brock Purdy ’s career-high five touchdown passes. Christian McCaffrey racked up 146 total scrimmage ...

The Indianapolis Colts host the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Live score updates, highlights, where to watch.

Philip Rivers starts again when he takes on the ferocious 49ers on "Monday Night Football." Here's score, highlights, stats ...

The Colts host the 49ers on tonight’s edition of Monday Night Football. The 49ers/Colts game begins at 8:15 p.m. ET on ESPN. Nope. But the Manning boys will return to ESPN2 for the Monday night ...

Breaking down the best wide receiver targets for the 49ers vs. Colts DraftKings MNF Showdown slate, including usage trends, ...

A meeting featuring two of the NFL's best in Christian McCaffrey and Jonathan Taylor will close Week 16 as the 49ers and Colts clash in a matchup with playoff implications.

The Sporting News is tracking live scoring updates and highlights for 49ers vs. Colts on "Monday Night Football." Follow for ...