There is emerging interest in adaptive platform trials for inflammatory bowel disease. In this Comment, we present the results of a workshop that was convened to consider the opportunities and ...

In this Journal Club, Minoli Perera reflects on a 2005 sequencing study by Cohen et al., who discovered two common loss-of-function mutations with large effects on plasma cholesterol levels thanks ...

It is important to understand the correlates of protection against SARS-CoV-2 and its variants for future vaccine design. Here, the authors show that the complement system enhances the antibody ...

Wondering what topics we're covering? We put together a collection with articles from other Nature Portfolio journals to highlight some of the areas we plan to publish in.

Inflammation is a biological response to harmful stimuli, such as pathogens, damaged cells or irradiation. It is a protective attempt by the organism to remove injurious stimuli and to initiate ...

The exact role FoxO3 in the regulation of cardiac regeneration remains unclear. Here, the authors show that FoxO3 negatively controls cardiomyocyte proliferation and heart regeneration in ...

A deep learning-guided de novo design identifies self-assembling peptides containing non-natural amino acids capable of killing multidrug-resistant bacteria and treating mice with acute intestinal ...

Evolution is the process of heritable change in populations of organisms over multiple generations. Evolutionary biology is the study of this process, which can occur through mechanisms including ...

Influenza virus is an infectious agent belonging to the virus family Orthomyxoviridae that causes a respiratory tract infection (influenza or 'flu') in vertebrates. There are three main species ...

CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing ...

The impact of senescent cells on remyelination is unknown. Here, the authors show that treatment with senolytics following demyelination enhances remyelination in young, but not aged mice, and ...

Anthony Davis and Dereck Lively II are both "progressing toward an in-season return" for the Dallas Mavericks as they continue to rehab injuries, according to NBA insider Marc Stein. Stein noted ...