Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

The Chicago White Sox are closing in on matching the 1962 New York Mets for the most losses in modern-day Major League ...

The Chicago White Sox staged a two-out rally in the 9th but fell to the San Diego Padres 3-2 in 10 on Friday. The Sox are ...

Fernando Tatis Jr.'s run-scoring hit leading off the 10th lifted the Padres to a 3-2 victory over the White Sox Friday.

Fernando Tatis Jr. wins game with double leading off the 10th inning; Joe Musgrove throws six scoreless innings ...

As the defeats continue to mount, the White Sox have joined the discussion of the most infamous baseball teams of all time.

Everything you need to know about the San Diego Padres vs. Chicago White Sox game on Sept. 21, including how to watch info, ...

The Chicago White Sox (36-117) begin a three-game series against the San Diego Padres (87-66) on Friday at PETCO Park. First ...

Red Sox right-hander Richard Fitts became the second pitcher in Major League Baseball history to accomplish a feat on Friday ...

This story was excerpted from Scott Merkin’s White Sox Beat newsletter. To read the full newsletter, click here. And ...

Oddsmakers have listed player props for Jurickson Profar, Andrew Vaughn and others when the San Diego Padres host the Chicago ...

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...