Introduction The PiSZ genotype results in less severe deficiency of alpha-1 antitrypsin (AAT) than PiZZ. Less is known about phenotypic and prognostic features. Methods We studied 699 PiZZ, 126 PiSZ ...
Correspondence to Professor Wim Janssens, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven 3000, Belgium; wim.janssens{at}uzleuven.be Rationale Estimating the ...
Background Chronic Obstructive Pulmonary Disease (COPD) is associated with persistent airway inflammation, which may be driven by an imbalance between pro-inflammatory macrophages and dysfunctional ...
Department of Respiratory Medicine, St James’s University Hospital, Leeds LS9 7TF, UK Correspondence to: Dr P K Plant, Department of Respiratory Medicine, Level 7, Gledhow Wing, St James’s University ...
Oral montelukast in acute asthma exacerbations: a randomised, double-blind, placebo-controlled trial
1 Department of Respiratory Medicine, Norfolk & Norwich University Hospital, Norwich, UK 2 School of Medicine Health Policy & Practice, University of East Anglia, Norwich, UK Correspondence to Dr ...
1 School of Medicine, Health Policy and Practice, University of East Anglia, Norwich, Norfolk, UK 2 Directorate of Medicine, Norfolk and Norwich University Hospital, Norwich, Norfolk, UK ...
2 Guy's and St Thomas' Foundation NHS Trust, London, UK 3 Greenwich Primary Care Trust, London, UK 4 Croydon Primary Care Trust, London, UK Background The COPD (chronic obstructive pulmonary disease) ...
Introduction The Improving Adult respiratory Care Together (ImpACT+) project is a collaboratively designed, commissioned integrated respiratory service in South Derbyshire which was fully implemented ...
Background Diabetes is associated with an increased risk of tuberculosis disease, but it is unclear whether a similar association exists between diabetes and latent tuberculosis infection (LTBI).
Introduction The promise of benefits from lung cancer screening is tempered by the false positive rate and the need to perform diagnostic procedures to determine the aetiology of the solitary ...
NICE guideline NG115 for COPD recommend Airways Clearance Techniques (ACTs) for people with excessive sputum but there have been no studies comparing different ACTs. Aim To compare Oscillatory ...
Background Telemonitoring (TM) for COPD has been shown to reduce hospital admissions in some but not all studies and its cost-effectiveness has been questioned. However, technical advances, real-time ...
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