Frontiers3y
Cathepsin D Variants Associated With Neurodegenerative Diseases Show Dysregulated Functionality and Modified α-Synuclein Degradation Properties
Hence, it is not surprising that genetic variants within the CTSD gene have been linked to neurodegenerative diseases, like Parkinson’s and Alzheimer’s disease (PD, AD), as well as the lysosomal ...
Frontiers5y
Increased P2X7 Receptor Binding Is Associated With Neuroinflammation in Acute but Not Chronic Rodent Models for Parkinson’s Disease
For fluorescent double staining, 50 μm vibratome sections were rinsed two times in PBS with 0.2% Triton X-100, followed by a 120 min blocking step in PBS with 10% donkey serum, 0.1% bovine serum ...