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49ers vs. Colts highlights: SF extends win streak to 5 games

The San Francisco 49ers offense is cruising and they were dominant in a win over the Indianapolis Colts. Here are the ...

Brock Purdy's career-high five TD passes power 49ers past Philip Rivers' Colts on 'Monday Night Football'

The Week 16 edition of "Monday Night Football" between the Indianapolis Colts (8-7) and the San Francisco 49ers (11-4) will ...

49ers thrash Colts behind Purdy’s 5 TD passes: Live updates and reaction from NFL ‘Monday Night Football’

With that latest touchdown from San Francisco, the Colts have now conceded more points (41) tonight than they have allowed in any game all season. The 49ers have piled up 433 yards of offense so far.

49ers’ Eddy Pineiro redeems pre-halftime doink with textbook field goal

Eddy Pineiro redeemed himself in the 49ers' MNF matchup against the Indianapolis Colts with a textbook field goal after a ...

Philip Rivers-Brock Purdy Battle on MNF Astounds NFL Fans as 49ers Beat Colts

Brock Purdy and the San Francisco 49ers earned a statement 48–27 road win over Philip Rivers and the Indianapolis Colts on Monday Night Football, as both quarterbacks put on an entertaining aerial ...

San Francisco 49ers vs Indianapolis Colts score, live updates, highlights today: Brock Purdy has 5 touchdown passes

The Indianapolis Colts host the San Francisco 49ers in NFL Week 16 action on 'Monday Night Football': Live score updates, highlights, where to watch.