He departed the third quarter of Cleveland’s 132-129 defeat to Philadelphia on Friday due to a right-knee injury.

The Cavs lost three consecutive games for the first time this season. But they feel going through this adversity is a positive.

Okoro's next chance to play will come against the Suns on Monday.

The Cavaliers will once again be without starter Evan Mobley and key contributor Isaac Okoro for Monday’s matchup against the visiting Phoenix Suns (3:30 p.m.

The Cleveland Cavaliers will still be without multiple key defensive players in their rematch against the Houston Rockets.

Okoro (shoulder) is questionable for Saturday's game against the Timberwolves, Evan Dammarell of DownEuclid.com reports.

Philadelphia aims to break its seven-game slide when the Philadelphia 76ers play Cleveland. Friday's matchup is the first this season for the teams.

Cleveland faces Houston in non-conference action. Saturday's matchup is the first of the season between the teams.

The Cleveland Cavaliers have largely avoided any major injuries up to this point in the season. However, the Wine and Gold are now dealing with a pair of critical player injuries, and some of them have already been ruled out for the Cavaliers' matchup against the Houston Rockets on Wednesday.

Cleveland; Monday, 7 p.m. EST BOTTOM LINE: Cleveland enters the matchup against Detroit after losing three in a row. The Cavaliers are 7-1 against division opponents. Cleveland ranks sixth in the Eastern Conference with 33.

After Wednesday’s bizarre loss in the final seconds, Darius Garland and the Cavaliers (-3.5) will attempt to get some revenge in Saturday’s rematch.

The Cavs have dropped two consecutive games for only the second time this season as they look to rebound Saturday night against the Houston Rockets.