Pediatric data on tigecycline remain limited, particularly for multidrug-resistant infections caused by gram-negative ...

Cancer cells frequently develop the ability to expel anticancer drugs before they can work—a phenomenon called multidrug resistance (MDR)—which is one of the leading reasons why chemotherapy fails in ...

Stenotrophomonas maltophilia (S. maltophilia) is a multidrug-resistant bacterium that can cause severe and life-threatening ...

Cancer cells frequently develop the ability to expel anticancer drugs before they can work -- a phenomenon called multidrug ...

A major European survey marks a significant milestone in the effort to control antimicrobial resistance (AMR), providing the ...

Multidrug resistance (MDR) remains one of the foremost obstacles to successful cancer therapy, arising when malignant cells evade the cytotoxic effects of structurally and functionally distinct agents ...

The discovery of a new preclinical compound with strong antifungal activity against multidrug-resistant pathogens is described in Nature. The drug, named mandimycin, is a member of a known family of ...

This study represents the first report of loading TIG onto hemoglobin (HB) nanoparticles. This system utilizes the iron ...

More than 10 million people fall sick with tuberculosis (TB) every year. The disease remains the world’s biggest infectious disease killers with an estimated 1.25 million annual deaths. The disease is ...

Multidrug resistance in fungal pathogens arises through a concerted array of biochemical and genetic adaptations that diminish the efficacy of existing antifungal agents. Central to this phenomenon is ...

A new class of antibiotics has demonstrated fast-acting, potent activity against two of the WHO’s priority pathogens. Researchers from the University of Liverpool (UK) have developed NovItex, a new ...

A preclinical study from Osaka Metropolitan University demonstrates that levofloxacin and cefiderocol both show therapeutic ...