The HLA Weed Science Lab has a new journal article available ahead-of-print in Weed Science. The article is co-authored by current and former members of the lab and features research conducted in ...
Kranthi Varala, and 9 co-authors from HLA, published the details of the new web-based regulatory gene discovery tool in the Proceedings of the National Academy of Sciences. Varala has a patent pending ...
Determining the specificity of HLA antibodies is arguably one of the most important contributions by the HLA laboratory today. For patients that have low-to-moderate levels of antibody, using a ...
The human leukocyte antigen (HLA) system has an important role in the regulation of the immune system; the HLA recognizes cells as ‘non-self’ or ‘self’ to prevent the body from attacking its own cells ...
Bone marrow or haemopoietic cell transplantation (HCT) is an effective treatment for multiple blood cancers. However, transplantation comes at a risk of acute or chronic graft-versus-host-disease ...
Somatic mutations in HLA genes were detected in the tumor data of five patients, and somatic HLA gene loss of heterozygosity was identified in the tumor data of five patients. Complete or partial ...
Reprogramming human regulatory T cell specificity with a novel anti-HLA-A2 chimeric antigen receptor
Engineering human regulatory T cells (Tregs) with a chimeric antigen receptor (CAR) targeting donor-derived human leukocyte antigen (HLA) is a promising strategy to induce immune tolerance to ...
We hypothesized that the combined use of leukoreduction and avoidance of infusion of ABO-incompatible antibodies or antigens would reduce both the need for HLA-matched platelets and the development of ...
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