UT Southwestern Medical Center has joined an international clinical trial studying whether a drug traditionally used to treat gout can help prevent kidney damage in patients with Type 1 diabetes.

In separate randomized controlled trials, allopurinol had no significant effect on kidney function decline. Urate-lowering therapy with allopurinol, a xanthine oxidase inhibitor, does not appear to ...

In a double-blind trial, patients with type 1 diabetes and early-to-moderate diabetic kidney disease were randomly assigned to receive allopurinol, which may slow the decline in the glomerular ...

This is the first study to assess the effect of allopurinol initiation on mortality in patients with CKD and concomitant gout, according to investigators. Allopurinol initiation and dose escalation ...

The drug is approved for use in adults, and rarely, in some children. Allopurinol’s drug classification is a xanthine oxidase inhibitor. Allopurinol oral tablets are available in two strengths: 100 ...