By making key signaling molecules called β-arrestins into druggable targets, scientists crack long-standing challenge

To function normally, nearly every cell in the human body relies on G-protein-coupled receptors (GPCRs) to receive and send ...
Nature

MBD2 promotes B cell differentiation and BCR signaling in systemic lupus erythematosus by regulating the LEF-1-PTEN-PI3K axis

Blood samples were obtained from individuals diagnosed with SLE and healthy counterparts. All individuals with SLE fulfilled the 1997 revised criteria for SLE established by the American College of ...
Business Wire

Leveragen Partners with Cell Signaling Technology to Advance Reagent Antibody Innovation with Proprietary Nanobody Technology

Nanobodies, or single-domain antibodies, are only about 10% the size of traditional antibodies, yet retain high target-binding affinity, exhibit enhanced tissue penetration, and can tackle ...