U.S. Secretary of State Marco Rubio is wrapping his up his second and final day at a Southeast Asian security conference with a high-stakes meeting with his Chinese counterpart as tensions grow over issues from trade to security and China’s support for Russia’s war in Ukraine.

U.S. Secretary of State Marco Rubio will meet Chinese Foreign Minister Wang Yi in Kuala Lumpur on Friday, the State Department said, in what will be the first in-person meeting of the two counterparts.

The meeting takes place on the sidelines of a Southeast Asian summit, where Washington and Beijing are each attempting to exert their influence.