A sextet of relievers effectively covered the nine innings Wednesday and the Tigers were able to get out of St. Louis with another series win.

Detroit Tigers Javier Baez successfully steals second base while St. Louis Cardinals infielder Nolan Gorman waits for the ball during the game between the St. Louis Cardinals and the Detroit Tigers in Busch Stadium in St. Louis on Wednesday, May 21, 2025.

Riley Greene homered and hit the winning RBI double in the ninth inning to help the Detroit Tigers beat the St. Louis Cardinals 5-4.

Riley Greene's single in the ninth inning scored Zach McKinstry from first to give the Tigers a 5-4 win over the Cardinals.

The Cardinals wrap up a home series Wednesday against the Tigers. First pitch is 12:15 p.m. Cardinals: Right-handed pitcher Andre Pallante (4-2, 4.11 ERA) Tigers: Left-handed pitcher Brant Hurter (1-0, 2.35 ERA)

Riley Greene had three hits, including a go-ahead RBI double in the ninth inning, to lead the Detroit Tigers to a 5-4 victory over the St. Louis Cardinals on Tuesday night at Busch Stadium. The Tigers (32-17) and Cardinals (27-22) have split the first two games of the three-game series.

Preview the May 21 matchup between the St. Louis Cardinals and Detroit Tigers with odds over/under, game spread, betting lines and more.